1, 3, 6, 8-Tetramethy1-2, 4, 5, 7 (1H, 3H, 6H, 8H) pyrimido [5, 4-<I>g</I>] pteridinetetrone and 1, 3, 5, 7-Tetramethy1-2, 4, 6, 8 (1H, 3H, 5H, 7H)-pyrimido [4, 5-<I>g</I>] pteridinetetrone

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A decentralized failure detection and isolation (FDI) methodology, which is robust with respect to model uncertainties and noise, is presented. Redundancy metrics are developed, and optimization problems are posed for the choices of robust parity relations. Closed-form solutions for some special failure cases are given. Connections are drawn with other disciplines, and the use of the metrics to...

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27 A 3,204 bp full-length cDNA of bovine NALP9 was cloned and its genomic organisation was 28 analyzed. The 2,988 bp open reading frame covers 9 exons and encodes a deduced protein of 996 29 amino acids containing Pyrin, Nacht and leucine-rich repeat domains like the human NALP gene 30 family members. Mapping with the WGRH5000 panel and fluorescence in situ hybridisation 31 assigned NALP9 in cl...

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1 Aims: Our main objective was to analyze individual determinants that lead middle-2 aged women to seek medical care for UI. 3 Methods: Observational longitudinal study among GAZEL cohort participants: 2640 4 women aged 50-62 completed a self-administered questionnaire at baseline. Eight 5 years later (2008) 2273 (86%) responded to a follow-up questionnaire. Seeking care 6 for UI was defined as...

rac-5′′-(4-Fluoro­benzyl­idene)-1′-(4-fluoro­phen­yl)-1′′-methyl-1′,2′,3′,5′,6′,7′,8′,8a′-octa­hydro­dispiro­[acenaphthyl­ene-1,3′-indolizine-2′,3′′-piperidine]-2,4′′(1H)-dione

In the title E isomer of the racemic compound, C37H32F2N2O2, the pyridinone ring adopts a twisted half-chair conformation with the N atom deviating by -0.355 (3) Å and with the methyl-ene C atom next to octa-hydro-indolizine moiety deviating by 0.415 (3) Å from the mean plane defined by other four atoms. In the octa-hydro-indolizine system, the pyrrolidine ring exhibits an envelope conformation...